Table 2. The linear relationship and corresponding coefficients as calculated between specialist and non-specialist observers using semi-automated software to identify the first pixel lying within a vessel and that representing the maximum relative cerebral blood volume (rCBVmax) non-vessel tumour value.
Analysis | Slope | Intercept | Correlation coefficient (r) |
Raw vessel with smallest pixel value | 0.98 | 0.40 | 0.993 |
Normalised vessel with smallest pixel value | 0.97 | 0.41 | 0.959 |
Raw rCBVmax | 0.98 | 0.43 | 0.997 |
Normalised nrCBVmax | 0.96 | 0.62 | 0.997 |
Data from both raw (unaltered) glioblastoma multiforme tumour series and tumour series normalised by the averaged rCBV in a region of contralateral white matter (nrCBVmax) are shown. A correlation coefficient of 1 with a gradient of 1 and intercept of 0 would correspond to absolute correlation. Values measured by the specialist can be predicted using the formula: specialist values=(slope)×(non-specialist values)+intercept.