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. 2013 Mar;68(3):351–358. doi: 10.6061/clinics/2013(03)OA11

Table 1.

Treatment groups and oral treatment regimens of the study participants. A randomized, double-blind, and placebo-controlled clinical trial of zinc, vitamin A, and glutamine supplementation in Brazilian shanty-town children from Fortaleza, CE, northeastern Brazil, during June 2000 and August 2004, with follow-up between June 2000 and December 2007.

Treatment Group Oral Treatment Regimen
Placebo Placebo*) (Placebo glutamine+Placebo zinc+Placebo vitamin A)
Glutamine Glutamine**)+Placebo zinc+Placebo vitamin A
Zinc Zinc†+Placebo glutamine+Placebo vitamin A
Vitamin A Vitamin A)+Placebo zinc+Placebo glutamine
Glutamine+Zinc Glutamine**)+Zinc†+Placebo vitamin A
Glutamine+Vitamin A Glutamine**)+Vitamin A)+Placebo zinc
Zinc+Vitamin A Zinc†+Vitamin A)+Placebo glutamine
Glutamine+Zinc+Vitamin A Glutamine**)+Zinc†+Vitamin A)
*

Isomolar glycine doses (8.3 g/day) over ten days started at one month of the study protocol; zinc vehicle (Tanjal juice) twice weekly for twelve months; placebo retinol = vitamin E (tocopherol 40 IU) each for four months at 0, four, and eight months.

**

Oral glutamine (16.2 g/day) for ten days starting at one month of the study protocol. † Zinc (zinc acetate) 40 mg twice weekly for 12 months.

Vitamin A (retinyl palmitate) 100,000 IU for children <12 months or 200,000 IU for children at least 12 months old, given as one dose at 0, four, and eight months of the study protocol.