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. 2012 Oct 5;104(20):1591–1598. doi: 10.1093/jnci/djs371

Table 3.

Trends in anal cancer incidence in the general population during 1980–2005

Category Annual percent change*, (95% CI), based on all anal cancer cases Annual percent change* (95% CI), with exclusion of HIV-infected anal cancer cases
Females
Total† 3.3 (3.0 to 3.7) 3.3 (2.9 to 3.6)
20–49 y 4.5 (3.8 to 5.3) 4.3 (3.6 to 5.1)
50–69 y 3.6 (3.0 to 4.1) 3.5 (3.0 to 4.0)
>70 y 2.4 (1.8 to 2.9) 2.4 (1.8 to 2.9)
Males
Total† 3.4 (2.9 to 3.9) 1.7 (1.2 to 2.3)
20–49 y 5.2 (4.2 to 6.2) 0.7 (−0.4 to 1.7)
50–69 y 3.1 (2.5 to 3.7) 2.0 (1.3 to 2.7)
>70 y 2.2 (1.6 to 2.8) 2.1 (1.5 to 2.7)
White 3.4 (2.8 to 3.9) 2.0 (1.5 to 2.6)
Black 4.3 (3.2 to 5.4) −0.6 (−2.0 to 0.8)

* Annual percent changes in anal cancer incidence rates were estimated using Joinpoint software. CI = confidence interval.

† Results are not presented for those aged 0–19 years because there were too few anal cancer cases (n = 8) in this age group to assess trends over time. However, this age group is included in the total and race-specific incidence rates. Results are presented stratified by race for males only, because HIV-infected anal cancer cases had little impact on anal cancer incidence rates in females.