Table 1.
Characteristics of women with ovarian cancer in the study
| Characteristic | BRCA1 (n = 129) | BRCA2 (n = 89) | No mutation (n = 1408) |
|---|---|---|---|
| Age at diagnosis, y, mean (range) | 51.1 (31–78) | 57.6 (34–73) | 57.7 (19–81) |
| Histology, No. (%) | |||
| Serous | 95 (73.6%) | 65 (73.0%) | 748 (53.1%) |
| Mucinous | 0 | 0 | 127 (9.0%) |
| Endometriod | 19 (14.7%) | 8 (8.9%) | 301 (21.4%) |
| Clear cell | 1 (0.8%) | 2 (2.3%) | 104 (7.4%) |
| Other | 14 (10.9%) | 14 (15.7%) | 128 (9.1%) |
| Stage, No. (%) | |||
| I | 7 (5.4%) | 6 (6.7%) | 267 (19.0%) |
| II | 23 (17.8%) | 4 (4.5%) | 241 (17.1%) |
| III | 79 (61.2%) | 60 (67.4%) | 692 (49.9%) |
| IV | 17 (13.2%) | 15 (16.9%) | 187 (13.3%) |
| Missing | 3 | 4 | 21 |
| Grade | |||
| I | 2 (1.6%) | 0 | 205 (14.6%) |
| II | 20 (15.5%) | 19 (21.4%) | 269 (19.1%) |
| III | 73 (56.6%) | 47 (52.8%) | 450 (32.0%) |
| Unknown | 34 (26.4%) | 23 (25.8%) | 484 (34.4%) |
| Year of diagnosis, mean (range) | 1999.6 (1995–2004) | 1999.3 (1995–2004) | 1999.5 (1995–2004) |
| Residence, No. (%) | |||
| Ontario | 109 (85.4%) | 68 (76.4%) | 1245 (88.4%) |
| Florida | 20 (15.5%) | 21 (23.6%) | 163 (11.6%) |
| Years of follow-up, mean (range) | 6.2 (6.9–12.0) | 6.4 (1.1–12.0) | 7.0 (0.3–12.0) |