Table 5. Best-corrected visual acuity changes from the baseline for each genotype.
| dbSNP ID | Gene | logMAR Vision Change at month 3 | P value | logMAR Vision Change at month 6 | P value |
|---|---|---|---|---|---|
|
rs1061170 |
CFH |
0.0817(83)/0.0465(17)/-0.1505(2) |
0.629 |
0.0835(83)/0.0641(17)/-0.0880(2) |
0.791 |
|
rs10490924 |
ARMS2 |
0.0689(8) /0.0471(37)/0.0873(57) |
0.867 |
0.1285(8) /0.1010(37)/0.0540(57) |
0.756 |
|
rs11200638 |
HTRA1 |
0.0947(9) /0.0342(37)/0.0920(56) |
0.731 |
0.1672(9) /0.0833(37)/0.0581(56) |
0.694 |
|
rs833069 |
VEGF-A |
0.0157(38)/0.0963(41)/0.1704(23) |
0.115 |
0.0542(38)/0.0757(41)/0.1166(23) |
0.807 |
| rs2071559 | KDR | 0.0762(43)/0.0449(47)/0.1472(12) | 0.618 | 0.0620(43)/0.0679(47)/0.1652(12) | 0.662 |
CFH=complement factor H; ARMS2=age related maculopathy susceptibility protein 2; HTRA1=high-temperature requirement A-1; logMAR=logarithm of minimum resolution; SNP=single nucleotide polymorphism; VEGF=vascular endothelial growth factor; KDR=kinase insert domain receptor. Data are mean logMAR vision change from baseline (n) for each genotype; major allele homozygous/heterozygous/risk allele homozygous.