Figure 4.

Reduction of inflammatory molecules by SRPIN340. A, B: Bars indicate average protein levels of monocyte chemoattractant protein (MCP)-1 and intercellular adhesion molecule (ICAM)-1 in the RPE-choroid complex obtained normal mice or CNV mice 3 days after laser photocoagulation combined with intravitreal injection of 0.1% DMSO or 20 pmol SRPIN340. Protein levels were measured with ELISA and normalized to total protein levels. Values are mean±SEM (n=8 to 10; n represents the number of eyes). *, p<0.05; †, p<0.01; ‡, p<0.001.