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. 2013 Mar 20;19:604–613.

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Copyright © 2013 Molecular Vision.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Importin 13 (IPO13) affected cell proliferation of cultured pterygium epithelial cells. Cell proliferation was assessed with 3-(4,5- dimethyl-2-thiazoyl)-2,5-di¬phenyl-2H-tetrazolium bromide (MTT) assay after transfection with pLV-flag, pLV-flag-IPO13, siRNA-CTR, and siRNA-IPO13 in the cultured pterygium epithelial cells (PECs). Overexpression of the IPO13 gene significantly increased the proliferation of PECs compared to pLV-flag; meanwhile, knockdown of the IPO13 gene significantly inhibited the cell proliferation of PECs compared to siRNA-CTR Data are represented as mean±SEM, n=4 in each group, *** p<0.001 versus pLV-flag or siRNA-CTR.