Table 9. Association study with haplotypes consisting of pairwise combination of six SNPs between cases and controls in the age-matching population.
| Haplotypesa | Allele frequencies | OR (95%CI)b | OR (95%CI)b | OR (95%CI)b | |||
| Cases | Controls | ||||||
| N | % | N | % | ||||
| G T T G C G | 189 | 32.1 | 156 | 26.5 | 1.00 | ||
| A C A G C A | 117 | 19.9 | 129 | 21.9 | 0.75 (0.54–1.04) | 1.00 | |
| A C A G C G | 89 | 15.1 | 89 | 15.1 | 0.83 (0.58–1.19) | 0.91 (0.62–1.33) | 1.00 |
| Others | 193 | 32.8 | 214 | 36.4 | 0.74 (0.56–0.99)c | 1.01 (0.73–1.38) | 1.11 (0.78–1.58) |
a
The sequence of the SNPs in the Haplotypes was rs2227983, rs2072454, rs17337023, rs1050171, rs1140475 and rs2293347;
b
ORs were adjusted for age, gender and lifestyle factors;
c
P<0.05.