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. 2013 Mar 29;8(3):e59771. doi: 10.1371/journal.pone.0059771

Table 2. Relationships between intratumoral/peritumoral CD163 expression and clinicopathologic features.

Variables Intratumoral CD163 expression Peritumoral CD163 expression
Average level or correlationcoefficient* P Average level or correlationcoefficient* P
Age, y 0.184 0.001 0.001 0.984
Gender, male vs female 0.025±0.036 vs. 0.017±0.024 0.155 0.037±0.040 vs. 0.033±0.040 0.499
Hepatitis B history, yes vs. no 0.023±0.032 vs. 0.025±0.040 0.665 0.037±0.043 vs. 0.037±0.027 0.963
Hepatitis B e antigen, positive vs.negative 0.023±0.035 vs. 0.023±0.034 0.933 0.040±0.036 vs.0.035±0.042 0.325
ALT −0.019 0.744 0.051 0.387
AST 0.047 0.429 0.136 0.021
γ-GT 0.048 0.409 0.139 0.017
ALP 0.125 0.033 0.103 0.079
Liver cirrhosis, yes vs. no 0.023±0.037 vs. 0.023±0.023 0.930 0.039±0.042 vs. 0.030±0.031 0.087
α-Fetoprotein 0.001 0.987 0.159 0.006
Tumor size 0.048 0.410 0.276 <0.001
Tumor encapsulation, complete vs. no 0.024±0.033 vs. 0.022±0.035 0.692 0.033±0.032 vs. 0.040±0.046 0.165
Microvascular invasion, yes vs. no 0.022±0.028 vs. 0.024±0.037 0.615 0.043±0.047 vs. 0.033±0.034 0.037
Tumor differentiation, I–II vs. III–IV 0.023±0.034 vs. 0.023±0.033 0.973 0.036±0.039 vs. 0.038±0.042 0.642
TNM stage, I vs. II/IIIA 0.024±0.039 vs. 0.022±0.027 0.516 0.033±0.035 vs. 0.041±0.044 0.085
*

If the clinicopathologic variable is a quantitative one, Spearman correlation analysis was performed and the correlation coefficient was presented.

Abbreviations: y, year; ALT, alanine aminotransferase; AST, aspartate aminotransferase; γ-GT, γ-glutamyl transpeptidase; ALP, alkaline phosphatase.