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. Author manuscript; available in PMC: 2014 Mar 28.
Published in final edited form as: J Med Chem. 2013 Feb 14;56(6):2178–2195. doi: 10.1021/jm301783x

Figure 11.

Figure 11

Binding of JDTic in human KOR crystal structure

(A) JDTic in the binding pocket of the crystal structure.

(B) Diagram of JDTic interaction in the binding pocket side chain at 4.5 Å cut-off. Reprinted with permission from reference 134. Copyright 2010 Nature.