Table 2.
| |||||
---|---|---|---|---|---|
Compd | Ke (nM)
|
μ/κ | δ/κ | ||
DAMGO, μ | DPDPE, δ | U69,593, κ | |||
2 (nor-BNI | 26 | 29 | 0.05 | 520 | 580 |
3 (JDTic) | 25 | 76 | 0.02 | 1250 | 3800 |
24a (KAA1) | 42 | 33 | 0.24 | 175 | 138 |
24b | 176 | 313 | 0.47 | 374 | 666 |
24c | 259 | 77 | 2.2 | 118 | 35 |
24d | 82 | 186 | 0.87 | 94 | 214 |
24e | 48 | 13 | 0.09 | 533 | 144 |
24f | 26 | 32 | 0.30 | 87 | 107 |
24g | 52 | 62 | 0.09 | 578 | 689 |
24h | 4.6 | 25 | 0.07 | 66 | 357 |
24i | 28 | 25 | 0.04 | 700 | 625 |