Skip to main content
. Author manuscript; available in PMC: 2014 Apr 28.
Published in final edited form as: J Control Release. 2013 Feb 4;167(2):200–209. doi: 10.1016/j.jconrel.2013.01.020

Figure 5.

Figure 5

(A) Gastrointestinal (GI) transfer efficacy of nanogel-drug conjugates, empty nanogels and free drugs in Caco-2 cell monolayers. (A) Percentage of drug transfer across the Caco-2 cell monolayer: (a) empty nanogel without drug, (b–d) nanogel-drug conjugates, and (e–f) free nucleoside analogs, Floxuridine and Gemcitabine (60–240 min incubation at 37°C). Data represents means ± SEM (n=3). (B) Permeability coefficients of nanogel-drug conjugates and free drugs calculated from the transfer data. Papp were compared for each formulation to determine their GI transport efficacy.