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Physicochemical characteristics of nanogels and drug conjugates
| Polymeric conjugate* | dh, nm (volume averaged) | PDI | ζ, mV |
|---|---|---|---|
| CPVA | 35 ± 1.3 | 0.36 | 0 ± 3.7 |
| CPVA-p4FLOX | 42 ± 6.4 | 0.41 | −8.5 ± 3.6 |
| CPVA-p4GEMC | 30 ± 2.4 | 0.25 | −17.9 ± 7.5 |
| CDEX | 44 ± 8.3 | 0.46 | −8 ± 4.0 |
| CDEX-p4GEMC | 34 ± 0.4 | 0.32 | −11.2 ± 7.0 |
Particle size (dh), polydispersity index (PDI) and zeta-potential (ζ) were measured in 1% solutions in water after 2h sonication. The results are average values ± SD of three measurements.
