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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Int J Neuropsychopharmacol. 2012 Aug 29;16(4):857–867. doi: 10.1017/S1461145712000703

Figure 5.

Figure 5

AAV-Cre-induced LepRb deletion in the adult dentate gyrus results in depression-like behavior. A. Tail suspension test. Immobility time was measured during the 6-min test period. n = 11 per group. **P < 0.01 compared to AAV-GFP treatment. B. Forced swim test. Immobility time was measured during the last 4 min of the 6-min test period. n = 8–10 per group. C. Saccharin preference was expressed as a ratio of the volume of saccharin solution intake to the volume of water intake for a 4-day test. n = 11 per group. *P < 0.05 compared to AAV-GFP treatment. D. Performance in the learned helplessness test. Left, mean escape latencies in six blocks of five trials. Right, number of failures to escape over the 30 trials. n = 9–12 per group. *P < 0.05, **P < 0.01, compared with the AAV-GFP, Shock control group. Data are presented as mean ± SEM.