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Model of the domain architecture in CNGC20. The CNBD (593–728) in part and the IQ domain are shown according to domain homologies (Bähler and Rhoads 2002, Letunic et al. 2012). The αB- and αC-helix of the CNBD are annotated from sequence homology to human CNGCs and HCN channels (Zagotta et al. 2003, Cukkemane et al. 2011). The NLS is highlighted, and predicted α-helical secondary structures for CNGC20 (Buchan et al. 2010) are illustrated below the sequence.
