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Intracellular [Ca2+]I-responses in type I cells harvested from normal rats (N), normal rats treated with ibuprofen (4 mg/kg/day for 8–10 days; N+I), rats exposed to hypoxia (380 Torr) for 8–10 days (CH), and CH rats treated with ibuprofen(CH+I). (A) Representative traces of [Ca2+]I from type I cells exposed to hypoxia (Po2 ∼36–40 Torr indicated by solid line). (B) Summary data (mean±SEM from 194–276 cells in each group; ***p<0.001 versus normal.
