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. Author manuscript; available in PMC: 2013 Mar 30.
Published in final edited form as: Expert Opin Drug Discov. 2012 Feb 10;7(3):207–216. doi: 10.1517/17460441.2012.660143

Figure 1. Demonstration of changes in CD68-positive macrophages (A) and Oil Red O staining (B) of aortic arch plaques from apoE−/− mice during atherosclerosis regression.

Figure 1

Left panels show aortic arch lesions of an apoE−/− mouse after 16 weeks on a high-fat diet; right panels show regressing aortic arch lesions 5 days after transplantation of the aortic arch from the same type of apoE−/− mouse in the left panels into a transgenic human apolipoprotein A-I expressing apoE−/− mouse. Magnification: 10×.