Table III.
Genotype distribution and odds ratios (ORs; 95% CI) for associations between HOXB13 genotypes and prostate cancer risk, stratified by family history of prostate cancer
Genotype | Cases (n=1,310) | Controls (n=1,259) | ORa,b | 95% CI | ||
---|---|---|---|---|---|---|
n | % | n | % | |||
First-degree relative with prostate cancer | ||||||
GG | 277 | (97.9) | 139 | (98.6) | 1.00 | (reference) |
GA | 6 | (2.1) | 2 | (1.4) | 1.49 | (0.30–7.50) |
No first-degree relative with prostate cancer | ||||||
GG | 1,016 | (98.9) | 1,115 | (99.7) | 1.00 | (reference) |
GA | 11 | (1.1) | 3 | (0.3) | 4.04 | (1.12–14.51) |
Adjusted for age.
Likelihood ratio test for interaction by family history: p=0.36.