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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Kidney Int. 2013 Jan 9;83(4):615–625. doi: 10.1038/ki.2012.410

Figure 7. RNase 7 disrupts the microbial membrane at low micromolar concentrations.

Figure 7

Atomic force microscopy demonstrates that 2.5 μM of RNase 7 disrupts the structural integrity of P. aeruginosa, E. coli, and E. faecalis after 45 minutes of exposure. A–C: Images of untreated uropathogens revealed intact cell morphology with a relatively smooth surface. D–F: uropathogens treated with RNase 7 showed loss of cellular integrity with membrane splitting and bleb formation (^). Each panel is 5 micron.