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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Acta Neuropathol. 2013 Jan 31;125(4):535–547. doi: 10.1007/s00401-013-1086-9

Fig. 1.

Fig. 1

Regional distribution of Aβ in fractions from the three-step extraction. After normalization within each individual, Aβ40 level in TBS fraction (a), TBS-TX fraction (b) and GuHCl fraction (c) and Aβ42 level in GuHCl fraction (d) are plotted by different brain areas with the average line of each area. In this and subsequent figures, blue areas are neocortical areas. Purple areas are limbic areas. Orange areas are subcortical areas. If two areas are not connected by a line on the upper portion of the graph, statistically significant difference was observed between these two areas. The p < 0.05 was considered significant; paired t test with Holm correction for multiple comparisons. TX TBS-TX