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Summary of Arsenic Trioxide in Vivo Activity Against Ewing Sarcoma Xenografts
| Xenograft Line | Median Time to Event | P-value | EFS T/C | Median RTV at End of Study | Tumor Volume T/C | Median Group Response | T/C Volume Activity | EFS Activity |
|---|---|---|---|---|---|---|---|---|
| SK-NEP-1 | 8.2 | 0.400 | 1.3 | >4 | 0.76 | PD1 | Low | Low |
| EW5 | 10.7 | 0.926 | 1.5 | >4 | 0.88 | PD2 | Low | Low |
| EW8 | 10.3 | 0.119 | 0.9 | >4 | 1.19 | PD1 | Low | Low |
| TC-71 | 6.2 | 0.952 | 1.0 | >4 | 0.97 | PD1 | Low | Low |
| CHLA258 | 17.2 | 0.452 | 1.0 | >4 | 0.88 | PD1 | Low | Low |
