Table 3.
Body weight (% change from starting body weight), total food (g) and water (mL) intake and total fecal (g) and urine (mL) output in rats during Indomethacin administration (days 5–12). Rats were gavaged daily with Water, Olive Oil, or Emu Oil (0.5 mL) throughout the experimental period and commenced daily gavage with water or Indomethacin (Indo; 8 mg/kg) on day 5. Rats were fasted overnight on day 11 and therefore day 12 body weight data was not included.
| Water + Water | Indo + Water | Indo + Olive Oil | Indo + Emu Oil | |
|---|---|---|---|---|
| Body weight (%) | 23.1 ± 0.8 | 1.6 ± 3.3*** | 6.0 ± 2.4 | 4.6 ± 2.0 |
| Food intake (g) | 132.8 ± 1.6 | 78.2 ± 4.9*** | 83.9 ± 4.3 | 77.9 ± 4.4 |
| Water intake (mL) | 416 ± 51.3 | 715.1 ± 72.1** | 651.7 ± 53.1 | 655.9 ± 66.1 |
| Fecal ouput (g) | 12.8 ± 0.4 | 10.1 ± 0.6** | 12.4 ± 0.5∧ | 12.4 ± 0.7∧ |
| Urine ouput (mL) | 104.2 ± 8.5 | 87.8 ± 3.1 | 85.4 ± 6.2 | 98.8 ± 7.3 |
Data are expressed as mean (%, g or mL) ± standard error of the mean. ***P < 0.001, **P < 0.01 compared to Water + Water; ∧ P < 0.05 compared to Indomethacin + Water.