Skip to main content
. Author manuscript; available in PMC: 2013 Mar 31.
Published in final edited form as: Neurobiol Dis. 2007 May 23;27(2):117–132. doi: 10.1016/j.nbd.2007.03.016

Fig. 2.

Fig. 2

Progression of the frequency of spontaneous recurrent motor seizures (SRMS) in different groups of chronically epileptic rats at 4, 5 and 6 months post-status epilepticus (SE). Note that, in epileptic rats receiving no grafts and epileptic rats receiving standard hippocampal fetal cell (HFC) grafts, the frequency of SRMS increases dramatically during this period. In contrast, in epileptic rats receiving grafts treated with BDNF, NT-3 and caspase inhibitor (CI) or grafts treated with FGF-2 and CI, the frequency of SRMS declines significantly. Comparison of the frequency of SRMS between different groups at 4, 5 and 6 months post-SE reveals that the frequency of SRMS in epileptic rats was similar in all groups at 4 months post-SE. However, at 1–2 months post-grafting, the frequency of SRMS in rats receiving grafts treated with BDNF, NT-3 and CI or grafts treated with FGF-2 and CI is considerably less than the frequency observed in epileptic rats receiving either no grafts or standard HFC grafts.