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. Author manuscript; available in PMC: 2013 Nov 15.

Published in final edited form as: J Biomech. 2012 Sep 25;45(16):2784–2790. doi: 10.1016/j.jbiomech.2012.08.042

Table 1.

Mean measures of whole bone composition, geometry and mechanical behavior. Values shown as mean (standard deviation).

	Control	NC1		NC3
	Control		Difference vs. Control (%)		Difference vs. Control (%)
Final Body Mass (g)	506 (39)	416 (39)	−18^*	408 (39)	−19^*
Tissue Mineral Content (mg)	23.2 (1.6)	18.6 (2.2)^*	−20^*	17.0 (1.5)⁺	−27^*⁺
Tissue Mineral Density (mg/cc)	937 (23)	864 (37)^*	−8^*	825 (41)⁺	−12^*⁺
Cortical Area (mm²)	8.4 (0.5)	7.3 (0.7)^*	−13^*	7.0 (0.6)^*	−17^*
Moment of Inertia (mm⁴)	17.5 (2.7)	14.3 (2.6)^*	−18^*	13.6 (2.8)^*	−22^*
Moment of Inertia Lin. A (mm⁴)	165 (33)	127 (29)^*	−23^*	120 (26)^*	−27^*
Moment of Inertia Lin. B (mm⁴)	90.1 (13.8)	68.0 (13.0)^*	−25^*	61.7 (12.0)^*	−32^*
Moment of Inertia Exp. (mm⁴)	449 (78)	273 (68)^*	−39^*	218 (49)^*⁺	−52^*⁺
Section Modulus (mm³)	5.3 (0.8)	4.4 (0.7)^*	−17^*	4.2 (0.7)^*	−20^*
Section Modulus Lin. A (mm³)	85.4 (12)	69.6 (11)^*	−19^*	66.0 (10)^*	−23^*
Section Modulus Lin. B (mm³)	26.9 (3.9)	20.9 (3.7)^*	−22^*	19.3 (3.0)^*	−28^*
Section Modulus Exp. (mm³)	131 (23)	81.5 (21)^*	−38^*	68.5 (14)^*⁺	−48^*⁺
Failure Moment (Nmm)	695 (94)	517 (72)^*	−26^*	469 (73)^*	−33^*
Bending Stiffness (Nmm²)	18100 (3600)	12400 (2800)^*	−32^*	11200 (2400)^*	−38^*
Post Yield Displacement (mm)	0.12 (0.15)	0.13 (0.14)	+8	0.14 (0.16)	+17
Effective Modulus (N/mm²)	1870 (570)	1560 (360)	−17	1500 (430)	−20^*

^*

Significantly different from Control;

⁺

significantly different from NC1 treatment group.