Table 1.
Oral palonosetron | IV palonosetron | |||||||
---|---|---|---|---|---|---|---|---|
0.25 mg (N = 155) | 0.50 mg (N = 160) | 0.75 mg (N = 158) | 0.25 mg (N = 162) | |||||
Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
Age (years) | 57.1 | 11.9 | 56.1 | 12.3 | 55.8 | 12.7 | 57.7 | 12.7 |
n | % | n | % | n | % | n | % | |
Gender | ||||||||
Male | 40 | 25.8 | 42 | 26.3 | 44 | 27.8 | 45 | 27.8 |
Female | 115 | 74.2 | 118 | 73.8 | 114 | 72.2 | 117 | 72.2 |
Ethnic group | ||||||||
White | 111 | 70.7 | 112 | 69.6 | 106 | 67.1 | 115 | 70.6 |
Black | 2 | 1.3 | 1 | 0.6 | 2 | 1.3 | 0 | 0.0 |
Hispanic | 43 | 27.4 | 45 | 28.0 | 49 | 31.0 | 45 | 27.6 |
Asian | 1 | .0.6 | 1 | 0.6 | 0 | 0.0 | 2 | 1.2 |
Other | 0 | 0.0 | 2 | 1.2 | 1 | 0.6 | 1 | 0.6 |
Main cancer type | ||||||||
Breast cancer | 81 | 52.3 | 82 | 51.3 | 82 | 51.9 | 85 | 52.5 |
Colon cancer | 11 | 7.1 | 8 | 5.0 | 12 | 7.6 | 7 | 4.3 |
Lung malignant neoplasm | 8 | 5.2 | 8 | 5.0 | 4 | 2.5 | 12 | 7.4 |
Chemotherapy history | ||||||||
Naïve | 95 | 61.3 | 91 | 56.9 | 93 | 58.9 | 96 | 59.3 |
Non-naïve | 60 | 38.7 | 69 | 43.1 | 65 | 41.1 | 66 | 40.7 |
Alcohol consumption | ||||||||
No | 101 | 65.2 | 86 | 53.8 | 88 | 55.7 | 94 | 58.0 |
Rarely | 30 | 19.4 | 41 | 25.6 | 43 | 27.2 | 34 | 21.0 |
Occasionally | 21 | 13.5 | 27 | 16.9 | 25 | 15.8 | 31 | 19.1 |
Regularly | 3 | 1.9 | 6 | 3.8 | 2 | 1.3 | 3 | 1.9 |
N number of patients in a specific group, n number of patients in the relevant category, % percentage based on N, SD standard deviation