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. 2012 Aug 10;75(4):979–989. doi: 10.1111/j.1365-2125.2012.04416.x

Table 1.

Slope estimates for QT correction factors

Slope estimates: mean of squared individual QTc-RR slopes*
Treatment QTcP QTcF QTcI QTcPL QTcIL
Placebo (n = 74) 0.0027 0.0028 0.0032 0.0027 0.0032
Exenatide (n = 74) 0.0030 0.0031 0.0041 0.0016 0.0026
*

A regression line was fitted to each subject QTc/RR pairs of four replicates at 21 pre-specified ECG assessment time points (09.00 h to 15.00 h on day 1, day 2 and day 3) by treatment (exenatide or placebo) and the mean of squared individual QTc-RR slope was calculated. QTcF, Fridericia QT correction; QTcI, individual QT correction-log linear; QTcIL, individual QT correction-linear QTcP, population QT correction-log linear; QTcPL, population QT correction-linear.