Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effect of increasing adult age on the predicted total drug clearance of CYP-selective probe drugs in Simcyp®. Data points represent mean clearances for all subjects (•), for female subjects only (▪) and for male subjects only (▴) in the n = 100 simulations
