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. 2012 Aug 24;75(4):1019–1028. doi: 10.1111/j.1365-2125.2012.04446.x

Figure 4.

Figure 4

Changes with increasing adult age in the physiological parameters that determine IVIVE of metabolic drug clearance in Simcyp®. Data points represent mean values for all subjects in the n = 100 simulations with caffeine