Table 1.

The main inclusion criteria for the four clinical trials

	Clinical trial A	Clinical trial B	Clinical trial C	Clinical trial D
Diagnosis	Probable AD	Probable AD	Probable AD	Probable AD
Age range (years)	50–80	50–85	55–85	≥50
MMSE score	16–26	16–26	15–26	12–24
mHIS score	≤4	≤4	≤4	≤4
Study partner	Yes	Yes	Yes	Yes
Cholinesterase inhibitor or memantine authorized	Yes	Yes	No	Only donepezil

MMSE, mini mental state examination; mHIS, modified Hachinski ischaemic scale.