Table 1.
Comparison of the characteristics of patients with end-organ damage receiving either nicardipine or labetalol
| Characteristic | Nicardipine (n=70) | Labetalol (n=71) |
|---|---|---|
| Mean age years±SD | 53.3±15.2 | 51.0±12.51 |
| Female | 51 | 52 |
| White | 21 | 13 |
| Black | 79 | 85 |
| Smoking history | 59 | 62 |
| Current smoker | 33 | 41 |
| Stimulant use history (cocaine or amphetamines) | 21 | 20 |
| Current stimulant use | 10 | 6 |
| Median BMI (IQR) | 29.7 (25.4, 35.0) | 29.6 (26.0, 35.3) |
| Median initial SBP (IQR) | 210.5 (197, 226) | 210 (200, 226) |
| Median initial DBP (IQR) | 115.5 (102.5, 126) | 116 (105.5, 126) |
| Median heart rate (bpm (IQR)) | 88 (76, 99) | 86 (75, 98) |
| Median respiratory rate (IQR) | 18 (16, 20) | 18 (17, 20) |
| Median pulse oximetry (%, (IQR)) | 98 (97, 100) | 99 (97, 100) |
| HX of HTN | 99 | 94 |
| Prior admission for HTN | 47 | 48 |
| HX of hyperlipidaemia | 42 | 29 |
| HX of DM | 41 | 26 |
| HX of CAD disease | 17 | 14 |
| HX of asthma | 14 | 20 |
| HX of on dialysis | 11 | 14 |
| HX of CHF | 7 | 14 |
| HX of MI | 10 | 7 |
| HX of stroke | 10 | 6 |
| HX of hepatitis | 3 | 11 |
| Median creatinine clearance (mg/dl (IQR)) | 70.5 (37.4, 99.5) | 77.3 (39.2, 104.9) |
| Median BNP (pg/dl (IQR)) | 385 (136, 3056) | 273 (141.0, 2184) |
| Troponin I (ng/ml (IQR)) | 0.1 (0.0, 0.2) | 0.0 (0.0, 0.2) |
| Abnormal ECG | 35 | 30 |
BMI, body mass index; DBP, dystolic blood pressure; SBP, systolic blood pressure.