Table 1.
The effect of exposure on mortality according to age
| Age (months) | On IPT* D/PYO | Exposed no IPT D/PYO | Unexposed D/PYO | MRR† IPT/unexposed | MRR‡ IPT/unexposed | MRR† No IPT/unexposed | MRR‡ No IPT/unexposed |
|---|---|---|---|---|---|---|---|
| 3–11 | 1/28 | 2/138 | 184/6204 | 1.40 (0.2 to 9.8) | 1.44 (0.2 to 11) | 0.51 (0.1 to 2.0) | 0.52 (0.1 to 2.1) |
| 12–35 | 1/306 | 10/509 | 226/14620 | 0.23 (0.0 to 1.7) | 0.23 (0.0 to 1.6) | 1.29 (0.7 to 2.4) | 1.28 (0.7 to 2.4) |
| 36–60 | 0/371 | 1/376 | 46/9888 | 0 | 0 | 0.57 (0.1 to 4.1) | 0.65 (0.1 to 4.6) |
| All | 2/706 | 13/1023 | 456/30713 | 0.30 (0.1 to 1.2) | 0.30 (0.1 to 1.2) | 0.97 (0.6 to 1.7) | 0.98 (0.6 to 1.7) |
Unexposed: community sample.
*Include unexposed children on IPT.
†MRR from a model with age as underlying time.
‡MRR from a model with age as underlying time, adjusted for gender, ethnicity, district, socioeconomic status, schooling of the mother and child crowding.
D/PYO, deaths/person-years of observation; IPT, isoniazid preventive therapy; MRR, mortality rate ratio.