TABLE 4.

Clinical HCC Patient’s Data and Distribution of AFP – /AdVhAFP-specific CD4⁺ T-cell Responses

ID*	Age†	Sex‡	Race§	Risk Factors‖	Stage¶	AFP Level (ng/ml)#	AFP-specific Responses**	AdVhAFP-specific Responses††
B12	52	M	White	Unknown	III	74.3	0.095	0.013
A3	69	M	White	Alcohol	IVa	3080	0.293	0.981
B11	60	M	White	Porphypia	IVa	4340	0.461	0.031
A4	62	M	Asian	HCV	IVb	10,800	0.987	0.033
B1	67	M	White	HBV	IVb	60,800	0.083	0.090
B10	59	M	White	HCV	IVa	463,040	0.327	1.000

Results are presented as P values for combined T_H1 cytokine responses.

Combined T_H1 cytokine—statistically significant T_H1 type responses calculated by combining trends in positivity responses for IL-2, IFN-γ, and TNF-α. Significant P values (P<0.05) are shown in bold font.

^*HCC patient identification.

^†Age of patient.

^‡M—male sex.

^§Race of patient.

^‖Risk factor identified for HCC, HCV, hepatitis C virus; HBV, hepatitis B virus.

^¶Stage of HCC disease.

^#AFP level—level AFP in the blood in time of leukapheresis.

^**AFP-specific responses: CD4⁺ T-cell responses to AFP protein-fed DC.

^††AdVhAFP-specific responses: CD4⁺ T-cell responses to AFP activated by AdVhAFP-engineered DC.