Table 4.

Results of subset analysis considering patient age, donor age, and donor source

	Grade 2-4 acute GVHD		Grade 3-4 acute GVHD		Chronic GVHD		Overall mortality
	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
Patients 50-59 y
MUD <50 y (n = 550)	1.00		1.00		1.00		1.00
MSD ≥50 y (n = 1013)	0.62 (0.53-0.73)	<.001	0.50 (0.41-0.62)	<.001	0.66 (0.56-0.77)	<.001	0.92 (0.81-1.05)	.22
Patients ≥60 y
MUD <50 y (n = 204)	1.00		1.00		1.00		1.00
MSD <67 y (n = 299)	0.61 (0.46-0.81)	<.001	0.69 (0.47-0.99)	.043	0.73 (0.56-0.96)	.025	0.78 (0.63-0.97)	.028
MSD ≥67 y (n = 94)	0.67 (0.45-0.99)	.04	0.62 (0.36-1.06)	.08	0.61 (0.39-0.93)	.023	1.23 (0.92-1.63)	.16