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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2012 Apr 27;84(4):1017–1023. doi: 10.1016/j.ijrobp.2012.02.020

Table 3.

Univariate analysis of associations between dosimetric factors and RP (n=72)

Variable RP grade 0-2
(n=57)		 RP grade 3-5
(n=15)		 P
value
V10 (previous RT plan) .019
 ≥33% 26 (44.1%) 12 (80.0%) -
 <33% 31 (55.9%) 3 (20.0%) -
V20 (previous RT plan) .082
 ≥23% 26 (44.1%) 11 (73.3%) -
 <23% 31 (55.9%) 4 (26.7%) -
V30 (previous RT plan) .082
 ≥16% 26 (44.1%) 11 (73.3%) -
 <16% 31 (55.9%) 4 (26.7%) -
V40 (previous RT plan) .088
 ≥11% 27 (45.8%) 11 (73.3%) -
 <11% 30 (54.2%) 4 (26.7%) -
MLD (previous RT plan) .019
 ≥12.4 Gy 25 (42.4%) 12 (80.0%) -
 <12.4 Gy 32 (57.6%) 3 (20.0%) -
V10 (SABR plan) .082
 ≥12% 26 (44.1%) 11 (73.3%) -
 <12% 31 (55.9%) 4 (26.7%) -
V20 (SABR plan) .082
 ≥6% 26 (44.1%) 11 (73.3%) -
 <6% 31 (55.9%) 4 (26.7%) -
V30 (SABR plan) .082
 ≥3% 26 (44.1%) 11 (73.3%) -
 <3% 31 (55.9%) 4 (26.7%) -
V40 (SABR plan) .088
 ≥2% 27 (45.8%) 11 (73.3%) -
 <2% 30 (54.2%) 4 (26.7%) -
MLD (SABR plan) .082
 ≥4.2 Gy 26 (44.1%) 11 (73.3%) -
 <4.2 Gy 31 (55.9%) 4 (26.7%) -
V10 (composite plan) .003
 ≥43% 24 (40.7%) 13 (86.7%) -
 <43% 33 (59.3%) 2 (13.3%) -
V20(composite plan) .003
 ≥30% 24 (40.7%) 13 (86.7%) -
 <30% 33 (59.3%) 2 (13.3%) -
V30 (composite plan) .022
 ≥22% 26 (44.1%) 12 (80.0%) -
 <22% 31 (55.9%) 3 (20.0%) -
V40 (composite plan) .019
 ≥15% 25 (42.4%) 12 (80.0%) -
 <15% 32 (57.6%) 3 (20.0%) -
MLD (composite plan) .022
 ≥16.5 Gy 26 (44.1%) 12 (80.0%) -
 <16.5 Gy 31 (55.9%) 3 (20.0%) -

Abbreviations: MLD = mean lung dose; RP = radiation pneumonitis; RT = conventional radiation therapy; SABR = stereotactic ablative radiation therapy; Vx = percent volume of lung exposed to at least x Gy.