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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Kidney Int. 2011 Jan 12;79(8):883–896. doi: 10.1038/ki.2010.526

Figure 1. Renal morphology and immunohistochemical staining for type IV collagen in the experimental groups.

Figure 1

A. Representative light microscopic appearance of glomeruli (PAS and PAM staining) and immunohistochemistry of Col4 for control rats (a, e, and i), STZ-induced diabetic SD rats, (b, f, and j), Zucker lean rats(c,g, and k), and Zucker fatty rats (d, h, and l). Bar = 100 μm.

B. Morphometric analysis of PAM positive staining area. The glomerular PAM positive area was measured as described in materials and methods. n=6 in each group, *P<0.05. C. Morphometric analysis of the glomerular expression of Col4. The glomerular staining area of Col4 was measured as described in materials and methods. n=6 in each group, *P<0.05. The data are expressed as means ± SD. Cont.= control rats, DM=STZ-induced diabetic SD rats, ZL=Zucker lean rats, ZF=Zucker fatty rats, ns=not significant.

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