Table 1.
Sample ID | Chip ID | Genetic Backgr. | Sex | Age at Surgery | Age at First Presentation | Age at Dgn. | Loc. | Status | MA | qRT-PCR |
01M/01C | PKh_03* | dna | m | 61.0 | dna | dna | dna | dna | x | 01M1 |
02M/02C | PKh_04* | dna | nk | nk | dna | dna | dna | dna | x | 02M* |
03M/03C | PKh_05* | dna | f | 53.0 | dna | dna | dna | dna | x | 03M*,† |
04-1M/04-1C | PKh_06* | dna | f | 72.0 | dna | dna | dna | dna | x | 04-1M* |
04-2M/04-2C | PKh_07* | dna | f | 72.0 | dna | dna | dna | dna | x | 04-2M* |
05M/05C | PKh_42* | dna | m | 65.0 | dna | dna | dna | dna | x | |
06M/06C | PKh_43* | dna | m | 56.0 | dna | dna | dna | dna | x | |
07M/07C | PKh_44* | dna | m | 62.0 | dna | dna | dna | dna | x | |
08B | PKh_40 | SDHB | f | 30.0 | 27 | 30 | A | Pr-NM | x | |
09B | PKh_10 | SDHB | m | 28.5 | 12 | 29 | E | Met | x | |
10B | PKh_11 | SDHB | m | 24.0 | 20 | 23 | E | Pr-M | x | |
11B | PKh_13 | SDHB | f | 46.0 | 28 | 46 | A | Pr-NM | x | |
12B | PKh_18 | SDHB | f | 9.0 | 8 | 9 | E | Mlt-NM | x | x |
13B | PKh_19 | SDHBP | m | 22.8 | 15–16 | 22 | E | Pr-M | x | |
14B | PKh_20 | SDHB | m | 26.6 | 8 | 9 | E | Met | x | x |
15B | PKh_21 | SDHB | m | 38.2 | 37 | 38 | E | Pr-M | x | |
16B | PKh_22 | SDHB | f | 45.6 | 41 | 42 | E | Mlt-NM | x | |
17-1B | PKh_27 | SDHB | f | 36.0 | 32 | 33 | E | Met | x | x |
17-2B | PKh_28 | SDHB | f | 36.2 | 32 | 33 | E | Met | x | |
18B | PKh_31 | SDHB | m | 52.0 | 40 | 41 | E | Met | x | |
19B | PKh_32 | SDHB | m | 12.0 | 13 | 13 | E | Pr-NM | x | |
20B | PKh_33 | SDHB | m | 31.0 | 30 | 30 | E | Pr-NM | x | x |
21B | PKh_34 | SDHB | m | 55.0 | 50 | 53 | E | Mlt-NM | x | x |
22B | PKh_36 | SDHB | m | 35.0 | no symptoms | 34 | E | Mlt-NM | x | |
23B | PKh_38 | SDHB | f | 34.8 | 10 | 18 | E | Met | x | |
24B | PKh_39 | SDHB | m | 17.1 | 15 | 15 | A | Mlt-NM | x | |
25D(HN) | PKh_37 | SDHD | m | 24.3 | 23 | 23 | HN | Pr-NM | x | |
26D(HN) | PKh_60 | SDHD | f | 34.0 | 34 | 34 | HN | Bi-M | x | |
27D(HN) | PKh_01 | SDHD | f | 49.3 | 28 | 28 | HN | Pr-NM | x | x |
28D(HN) | PKh_02 | SDHD | f | 61.1 | 60 | 60 | HN | Pr-NM | x | |
29D(AT) | PKh_08 | SDHD | m | 16.0 | 16 | 16 | A | Pr-NM | x | x |
30D(AT) | PKh_09 | SDHD | f | 31.0 | 31 | 31 | A | Pr-NM | x | x |
31-1D(AT) | PKh_24 | SDHD | f | 26.6 | 23 | 24 | A | Mlt-NM | x | |
31-2D(HN) | PKh_25 | SDHD | f | 26.6 | 23 | 24 | HN | Mlt-NM | x | x |
31-3D(HN) | PKh_29 | SDHD | f | 27.1 | 23 | 24 | HN | Mlt-NM | x | |
32D(HN) | PKh_58 | SDHD | m | 48.0 | 48 | 48 | HN | Bi-NM | x | x |
33D(AT) | PKh_26 | SDHD | m | 61.4 | 58 | 58 | A | Pr-NM | x | x |
34D(HN) | PKh_59 | SDHD | f | 29.0 | 29 | 29 | HN | Mlt-NM | x | x |
35-1D(AT) | PKh_35 | SDHD | m | 31.8 | 31 | 25 | A | Mlt-NM | x | x |
35-2D(AT) | PKh_41 | SDHD | m | 32.6 | 31 | 25 | E | Mlt-NM | x | |
36V | PKh_57 | VHL | f | 24.8 | no symptoms | 17 | A | Bi-NM | x | |
37-1V | PKh_55 | VHL | m | 22.7 | 18 | 22 | A | Bi/Mlt-NM | x | |
37-2V | PKh_56 | VHL | m | 23.1 | 18 | 22 | A | Bi/Mlt-NM | x | |
38V | PKh_54 | VHL | m | 16.1 | 16 | 16 | A | Bi/Rec-NM | x | |
39V | PKh_53 | VHL | m | 28.6 | no symptoms | <28 | A | Pr-NM | x | |
40V | PKh_52 | VHL | m | 13.1 | no symptoms | 12 | A | Bi-NM | x | |
41V | PKh_45 | VHL | f | 42.8 | nk | <41 | A | Pr-NM | x | |
42V | PKh_46 | VHL | m | 29.4 | 29 | 29 | A | Bi/Mlt-NM | x | |
43V | PKh_47 | VHL | f | 42.6 | nk | <15 | A | Bi-NM | x | x |
44V | PKh_48 | VHL | m | 39.2 | nk | 39 | A | Pr-NM | x | x |
45V | PKh_49 | VHL | m | 30.6 | <30 | 30 | A | Bi-NM | x | |
46V | PKh_50 | VHL | m | 33.1 | 4 | 5 | A | Bi/Mlt/Rec-NM | x | x |
47V | PKh_51 | VHL | m | 18.9 | no symptoms | 16 | A | Bi/Mlt-NM | x | |
48V | dna | VHL | m | 33.5 | nk | nk | A | Bi-NM | x |
A indicates adrenal; f, female; backgr., background; Bi, bilateral; dgn., diagnosis; dna, does not apply; E, extra-adrenal; ID, identifier; loc., location; m, male; M, metastatic; MA, microarray; met, metastases; Mlt, multifocal primary; nk, not known; NM, non-metastatic; Pr, primary; Rec, recurrent; SDHDP, SDHD-polymorphism; x indicates sample used in experiment specified by column heading; patients 25, 31, and 40 were first-degree relatives to 35, 33, and 47, respectively.
Applies to normal medulla samples.
Included for ACTR10, EGLN3, F8, LGR5, MPP6, NEFM, SLC18A1, TMEM130, and VSNL1.