Table 4.
Overall Survival (OS) from Time of First High-Risk FISH Analysis for the Entire Cohort by Mutational Analysis
| N | Median | (95% CI) (Years) | 3 Years | Log Rank P | HR | 95% CI | |
|---|---|---|---|---|---|---|---|
| OS: All Patients | 66 | 5.4 (3.1,5.6+) | 67 (53, 84) | ||||
| OS, By Mutational Status | |||||||
| Low IGVH Mutation (< 2) | 50 | 4.5 (2.0, 6.2+) | 55 (39, 78) | .02 | 1.00 | - | |
| High IGVH Mutation (2+) | 16 | NR | 100 (100, 100) | .15 | (0.02, 1.2) | ||
| OS: Patients With del(11q) | |||||||
| Low IGVH Mutation (< 2) | 28 | 11.3 (11.3, 19.9+) | 70 (49, 98) | .31 | 1.00 | - | |
| High IGVH Mutation (2+) | 11 | NR | 100 (100, 100) | .37 | (0.04, 3.1) | ||
| OS: Patients With del(17p) | |||||||
| Low IGVH Mutation (< 2) | 22 | 1.9 (1.2, 5.6+) | 34 (15, 78) | .02 | 1.00 | - | |
| High IGVH Mutation (2+) | 5 | NR | 100 (100, 100) | a |
Values for median survival are in years. Other values are survival probability (95% CI).
Abbreviations: Hazard ratio could not be estimated because no deaths occurred in the patients with del(17p) mutated IGVH sequence.