Table 2.
Summary information for selected SNPs at 15q25 from meta-analysis of association with the Smoking Quantity (SQ) phenotype. Our study is referred to as OX-GSK. Information for all SNPs spanning the 15q25 locus in our genomewide analysis is given in Supplementary Table 2.
| SNP (rs ID) | Chr | Position | Coded Allele |
Coded Allele MAF |
OX-GSK | TAG | ENGAGE | Combined | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| P-value | heterozygosity P-value |
P-value | P-value | P-value | Beta | SE | |||||
| rs588765 | 15 | 76652480 | T | 0.43 | 1.74×10−3 | 0.50 | NA | NA | NA | NA | NA |
| rs16969968 | 15 | 76669980 | G | 0.65 | 1.64×10−18 | 0.86 | 1.85×10−27 | 1.53×10−23 | 4.29×10−65 | −0.078 | 0.0046 |
| rs1051730 | 15 | 76681394 | G | 0.66 | 9.45×10−19 | 0.68 | 3.62×10−27 | 9.98×10−25 | 1.71×10−66 | −0.079 | 0.0046 |
| rs6495308 | 15 | 76694711 | T | 0.77 | 3.30×10−10 | 0.10 | 7.99×10−24 | 1.60×10−13 | 5.82×10−44 | 0.073 | 0.0052 |