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Variation in T1 weighted signal contrast is typically achieved through manipulation of acquisition parameters and pulse sequence type. For example, (a) SPGR TE/TR/flip angle = 1ms/15ms/3 degrees; (b) SPGR TE/TR/flip angle = 1ms/15ms/18 degrees; (c) IR TE/TR/TI = 10/2500/500ms; (d) IR TE/TR/TI = 10/1800/850ms.
