Table 3. Metabolite Differences Between Patient Groups (µmol/g of tissue).
Metabolite Category | Non-Failing | Failing | Post-VAD |
Glucose/Sugars | |||
Glucose | 1.49±0.54 | 0.72±0.61* | 1.46±0.61** |
Lactate | 11.2±3.69 | 5.72±5.76* | 15.6±5.54** |
Amino Acids | |||
Glutamine | 7.46±1.64 | 4.74±1.99* | 5.22±0.53 |
Alanine | 4.88±1.44 | 2.13±1.57* | 2.83±1.6 |
Aromatic Amino Acids | 10.8±1.64 | 8.29±2.80* | 7.19±3.23 |
Other | |||
Total Creatine | 10.4±1.97 | 4.70±3.32* | 5.20±3.4 |
Succinate | 3.55±0.91 | 2.19±1.23* | 3.48±1.25 |
Metabolite differences between non-failing and failing hearts (* = p<0.05) and failing and post-VAD hearts (** = p<0.05).