Skip to main content
. 2013 Apr 1;8(4):e59908. doi: 10.1371/journal.pone.0059908

Figure 2. Coding mutations in each of the 15 CB iPSC lines.

Figure 2

Number of coding SNVs (A) and nonsynonymous coding SNVs (B) in each line compared to the parent cord blood cells. MK: iPSC lines generated with OCT4, SOX2, MYC and KLF; OS: iPSC lines generated with OCT4 and SOX2; Z: iPSC lines generated with OCT4, SOX2; and ZSCAN4. The use of OSZ appears to decrease the coding SNV load in iPSC lines compared to the OSMK control (P>0.05) (A), while OSZ iPSC lines harbor significant fewer number of nonsynonymous coding SNVs relative to the OSMK control (P<0.05) (B).