Table 4.
Effect of −514C>T LIPC Genotypes on biochemical analytes among Controls and Patients and according to gender within the 2 groups
| Controls (n = 117) | ||||
|---|---|---|---|---|
| Parameters | CC (n = 66) | CT (n = 40) | TT (n = 11) | P value |
| HDL-C (mg/dl) | 48.45 ± 10.43 | 51.63 ± 9.02 | 54.0 ± 7.81 | 0.105 |
| HDL2-C (mg/dl) | 12.36 ± 5.99 | 12.7 ± 6.99 | 13.45 ± 5.39 | 0.859 |
| HDL3-C (mg/dl) | 36.09 ± 8.14 | 38.92 ± 5.79 | 40.55 ± 4.25 | 0.049 |
| LDL-C (mg/dl) | 121.65 ± 27.08 | 118.60 ± 20.50 | 120.18 ± 21.50 | 0.825 |
| sdLDL (mg/dl) | 21.02 ± 10.94 | 19.2 ± 8.03 | 19.55 ± 8.50 | 0.635 |
| Males (n = 81) | ||||
| CC (n = 51) | CT (n = 25) | TT (n = 5) | ||
| HDL3-C (mg/dl) | 34.51 ± 7.23 | 37.24 ± 5.22 | 41.4 ± 4.62 | 0.037 |
| Apo A1 (g/l) | 1.18 ± 0.16 | 1.26 ± 0.14 | 1.31 ± 0.92 | 0.047 |
| Patients (n = 119) | ||||
| CC (n = 66) | CT (n = 40) | TT (n = 13) | ||
| HDL-C (mg/dl) | 35.36 ± 7.69 | 34.23 ± 9.37 | 34.85 ± 8.56 | 0.795 |
| HDL2-C (mg/dl) | 10.44 ± 4.12 | 11.2 ± 5.21 | 10.15 ± 4.49 | 0.645 |
| HDL3-C (mg/dl) | 24.92 ± 5.67 | 23.03 ± 6.72 | 24.69 ± 5.27 | 0.281 |
| LDL-C (mg/dl) | 100.59 ± 31.97 | 104.68 ± 31.98 | 97.23 ± 30.02 | 0.710 |
| sdLDL (mg/dl) | 13.98 ± 7.26 | 14.45 ± 8.43 | 13.08 ± 8.09 | 0.854 |
P values calculated using one way analysis of variance (ANOVA)