Table 3.
Summary of published metal ion studies
| Study | Implant | Number of patients | Followup (months) | Median CoS (range) | Median CrS (range) | Detection method |
|---|---|---|---|---|---|---|
| Witzleb et al. [42] | BHR | 23 | 24 | 4.28 μg/L (range not reported) |
5.12 μg/L (range not reported) |
GF-AAS |
| Kim et al. [22] | Conserve Plus | 97 | 24 | 1.08 μg/L (0.44–7.13) |
1.64 μg/L (0.47–10.95) |
ICPMS |
| Allan et al. [1] | Cormet | 16 | 36 | 2.08 μg/L (range not reported) |
3.55 μg/L (range not reported) |
ICPMS |
| Moroni et al. [31] | BHR | 20 | 24 | 0.75 μg/L (0.08–8.96) |
1.73 μg/L (0.69–7.24) |
GF-AAS |
| Moroni et al. [32] | BHR | 20 | 60 | 0.72 μg/L (0.30–13.50) |
1.63 μg/L (0.49–10.67) |
GF-AAS |
| Current study | Conserve Plus | 182 | 12–165 | 1.13 μg/L (0.15– 175.30) |
1.49 μg/L (0.06–88.70) |
ICPMS |
BHR = Birmingham Hip Replacement; GF-AAS = graphite furnace atomic absorption spectrometry; ICPMS = inductively coupled plasma mass spectrometry.