Figure 7.

(I) Time evolution of model cell activities during “cautious” mode (when ITCd activation is much higher than ITCv activation): the system is biased to prevent extinction. (Parameters: strength of inhibition f_I = 3.0; input from IL to ITCd E_ILd = 5; input from IL to ITCv E_ILv = 2). (II) Time evolution of model cell activities during “rapid switch” mode (when ITCv activation is much higher than ITCd activation): the system is biased to enhance extinction. (Parameters: strength of inhibition f_I = 3.0; input from IL to ITCd E_ILd = 0; input from IL to ITCv E_ILv = 5). Each plot shows the temporal evolution of a single cell over four consecutive epochs, with the y-axis representing strength of activation. In the first and third epochs, the CS signals, co-occur with R⁺, the US. In the second and fourth epochs, the CS signals are presented without R⁺. The red dotted lines indicate presence of R⁺. The green lines indicate extinction epochs in which R⁺ = 0.