Table 3.
Category | Gene | log2 (fold change) | Gene | log2 (fold change) | Gene | log2 (fold change) | Gene | log2 (fold change) | Gene | log2 (fold change) | Gene | log2 (fold change) | Gene | log2 (fold change) |
Nutrient/stress response | ||||||||||||||
HSP12 | 2.912 | HSP104 | 1.229 | ECM4 | 0.954 | SPG4 | 0.765 | HMX1 | 0.606 | DDR2 | 2.872 | ALD3 | 1.200 | |
MOH1 | 0.933 | TPS2 | 0.756 | YMR090W | 0.602 | HSP26 | 2.805 | SOL4 | 1.159 | HOR2 | 0.907 | DUR1,2 | 0.753 | |
MSN4 | 0.602 | HUG1 | 2.404 | CRG1 | 1.139 | USV1 | 0.898 | HSP31 | 0.746 | PHO12 | –0.602 | TMA10 | 1.817 | |
ADR1 | 1.133 | TMA17 | 0.896 | RNY1 | 0.741 | PHO11 | –0.604 | MSC1 | 1.803 | NTH1 | 1.131 | UBC5 | 0.893 | |
YOR052C | 0.731 | SPL2 | –0.660 | TSL1 | 1.793 | ATG8 | 1.129 | HOR7 | 0.882 | YJL144W | 0.711 | ZRT1 | –0.760 | |
GAD1 | 1.753 | CTT1 | 1.104 | PUT1 | 0.874 | AHA1 | 0.691 | RSN1 | –0.805 | HSP42 | 1.664 | FRE7 | 1.045 | |
SOM1 | 0.860 | YNR014W | 0.677 | AAH1 | –0.805 | GLK1 | 1.635 | PRB1 | 1.037 | ATH1 | 0.852 | YNL134C | 0.676 | |
PHM6 | –0.815 | TFS1 | 1.522 | NCE103 | 1.036 | SSA3 | 0.833 | GRX1 | 0.664 | HMS2 | –0.832 | PNC1 | 1.470 | |
GTT1 | 1.022 | IGD1 | 0.826 | EDC2 | 0.637 | SSA4 | 1.465 | SSE2 | 1.009 | YJR096W | 0.811 | SPI1 | 0.631 | |
GRE1 | 1.394 | GAC1 | 1.004 | TPS1 | 0.808 | RAD51 | 0.630 | GCY1 | 1.382 | PLM2 | 0.990 | GPD1 | 0.802 | |
RCN2 | 0.630 | HSP78 | 1.338 | MCR1 | 0.980 | GRE3 | 0.800 | YAP6 | 0.628 | PGM2 | 1.317 | YDL124W | 0.968 | |
CAR2 | 0.796 | PEP4 | 0.620 | XBP1 | 1.304 | PRX1 | 0.966 | PUT4 | 0.784 | YOR289W | 0.614 | YDR034W-B | 1.255 | |
SDS24 | 0.962 | YKL151C | 0.771 | DAN4 | 0.609 | |||||||||
Mating and sporulation | ||||||||||||||
AGA2 | 2.532 | GPG1 | 1.320 | CWP1 | 1.064 | EMI2 | 0.694 | TPK1 | 0.606 | MFA1 | 1.555 | PRM1 | 1.227 | |
BAR1 | 1.034 | GSM1 | 0.678 | PST2 | 0.604 | HBT1 | 1.552 | UBI4 | 1.223 | PRM6 | 0.931 | SPO12 | 0.651 | |
TCB2 | –0.726 | FIG1 | 1.450 | FIG2 | 1.195 | RMD5 | 0.784 | FUS1 | 0.642 | PRM7 | –0.945 | |||
GSC2 | 1.377 | AFR1 | 1.145 | YOR338W | 0.755 | AGA1 | 0.641 | RIM4 | 1.363 | PRM2 | 1.108 | FUS2 | 0.737 | |
PTP2 | 0.628 | MFA2 | 1.345 | STE2 | 1.102 | KAR4 | 0.712 | SPS100 | 0.616 | |||||
Carbohydrate metabolism | ||||||||||||||
GPH1 | 2.447 | HXT6 | 1.136 | GND2 | 0.789 | PFK26 | 0.679 | HXK1 | 1.863 | HXT7 | 1.130 | YBR056W | 0.723 | |
YLR345W | 0.673 | AMS1 | 1.699 | GSY2 | 1.056 | HXT5 | 0.720 | RKI1 | –0.616 | NQM1 | 1.423 | PIG1 | 0.914 | |
CIT1 | 0.717 | HXT1 | –0.710 | GPM2 | 1.278 | GSY1 | 0.868 | UGP1 | 0.695 | GDB1 | 1.252 | GIP2 | 0.842 | |
PYK2 | 0.695 | GLC3 | 1.192 | PCK1 | 0.789 | GUT2 | 0.689 | |||||||
Cell wall | ||||||||||||||
YGP1 | 2.467 | KDX1 | 1.176 | YPS6 | 1.017 | DSE1 | –0.650 | EGT2 | –0.718 | YPS5 | 1.204 | PRM5 | 1.103 | |
PIR3 | 0.988 | SUN4 | –0.685 | PRY3 | –1.042 | |||||||||
Autophagy | ||||||||||||||
LAP4 | 1.229 | DCS1 | 0.981 | ATG34 | 0.878 | PAI3 | 0.738 | DCS2 | 1.025 | ALD2 | 0.892 | ATG33 | 0.743 | |
ATG19 | 0.732 | |||||||||||||
Mitochondrial | ||||||||||||||
FMP16 | 1.902 | CYC7 | 1.036 | AIM17 | 0.984 | MRP8 | 0.702 | COX5B | 0.656 | CTP1 | –0.806 | STF1 | 1.622 | |
INH1 | 0.993 | OM45 | 0.918 | UIP4 | 0.699 | MPM1 | 0.644 | ALD4 | 1.305 | FMP33 | 0.986 | YNL200C | 0.892 | |
GOR1 | 0.664 | SDH2 | 0.633 | |||||||||||
Other | ||||||||||||||
YPR160W-A | 2.593 | YDR042C | 1.159 | VMR1 | 0.901 | YMR181C | 0.747 | PIC2 | 0.641 | SFG1 | –0.605 | YGL101W | –0.823 | |
YIL082W | 2.021 | YJL133C-A | 1.145 | LEE1 | 0.901 | YLR312C | 0.732 | YNL058C | 0.637 | LIA1 | –0.614 | YBR191W-A | –0.862 | |
RTN2 | 1.860 | ROM1 | 1.143 | YOR343C | 0.867 | YBR139W | 0.726 | YPL088W | 0.632 | BSC1 | –0.615 | YMR317W | –0.907 | |
YMR196W | 1.797 | BOP2 | 1.142 | PET10 | 0.858 | YOR192C-C | 0.709 | YHR052W-A | 0.624 | NIP7 | –0.629 | PLB2 | –0.923 | |
NCA3 | 1.724 | CRG1 | 1.139 | YLR307C-A | 0.822 | YER053C-A | 0.692 | YPR145C-A | 0.623 | LYS1 | –0.633 | YMR046W-A | –1.003 | |
RNR3 | 1.683 | RTS3 | 1.115 | YLR108C | 0.798 | COS12 | 0.690 | YCL076W | 0.622 | HTB2 | –0.654 | YOL014W | –1.206 | |
PHM8 | 1.500 | GSP2 | 1.097 | PRY1 | 0.787 | BNA2 | 0.685 | PEX27 | 0.617 | YBL029W | –0.688 | YFR052C-A | 1.498 | |
YKR011C | 1.053 | YDL247W-A | 0.783 | GAP1 | 0.684 | YLR042C | 0.617 | YPR002C-A | –0.708 | YNR034W-A | 1.365 | PBI2 | 0.993 | |
YBR201C-A | 0.780 | YOR114W | 0.673 | VPS73 | 0.614 | ADE17 | –0.712 | RTC3 | 1.332 | SRL3 | 0.987 | CUR1 | 0.769 | |
YNL115C | 0.670 | REC104 | 0.611 | HTA2 | –0.719 | YHR138C | 1.263 | ECL1 | 0.986 | YCL021W-A | 0.767 | GGA1 | 0.663 | |
YHR007C-A | 0.608 | YNL217W | –0.729 | YLR149C | 1.179 | YCL042W | 0.954 | YDR379C-A | 0.758 | HER1 | 0.657 | RGC1 | 0.603 | |
ARG8 | –0.764 | YBR085C-A | 1.178 | BTN2 | 0.926 | YCL049C | 0.758 | YBR053C | 0.652 | YHR177W | 0.602 | YDL038C | –0.799 |
High-resolution gene expression analysis of the smt3allR mutant revealed that 261 genes were over- or underexpressed as compared to parental cells.