Figure 3.

γ-Catenin protein expression correlates with β-catenin protein expression in AML blasts. (a) Representative western blot images demonstrating the localization of γ-catenin and β-catenin (β-Cat) protein within normal CD34⁺ HSPC and AML patient blasts. Protein loading and fraction purity were assessed by actin and histone H1 detection. (b) Summary data showing the correlation between total γ-catenin protein and total β-catenin protein in AML blasts (n=59; arbitrary densitometric units). (c) Summary data showing the correlation between cytosolic levels of β-catenin and the corresponding level of nuclear β-catenin protein in AML blasts (n=59; arbitrary densitometric units).