Table 1.
Characteristics of participants with rapid- v. non-rapid-cycling bipolar disorder at the start of double-blind therapy
| Characteristic | Rapid-cycling group (n = 25) | Non-rapid-cycling group (n = 56) | P a |
|---|---|---|---|
| Male gender, % (n/N) | 64.0 (16/25) | 41.1 (23/56) | 0.06 |
| Age, years: mean (s.d.) | 35.3 (10.0) | 38.8 (12.8) | 0.23 |
| Illness duration, years: mean (s.d.) | 17.2 (10.0) | 20.0 (11.9) | 0.32 |
| Depressive episode duration, months: mean (s.d.) | 13.3 (15.3) | 4.0 (19.3) | 0.87 |
| Prior depressive episodes, mean (s.d.) | 22.8 (43.7) | 6.6 (6.4) | 0.008 |
| Prior hypomanic episodes, mean (s.d.) | 45 (56.2) | 9.0 (13.4) | <0.0005 |
| Hamilton Rating Scale for Depression score baseline, mean (s.d.) | 7.2(6.1) | 5.4 (4.0) | 0.13 |
| Young Mania Rating Scale score baseline, mean (s.d.) | 1.3(2.8) | 0.8 (1.7) | 0.27 |
a
P-values are from Student's t-test except for gender, which is from χ2.