Table 2.
Baseline characteristics and demographics by BMI*
| NERD | EO | |||||
|---|---|---|---|---|---|---|
| BMI, kg/m2 | BMI, kg/m2 | |||||
| <25 | 25 to <30 | ≥30 | <25 | 25 to <30 | ≥30 | |
| Variable | N = 267 | N = 296 | N = 363 | N = 821 | N = 1531 | N = 1669 |
| Gender, male, n (%) | 61 (22.8) | 115 (38.9) | 89 (24.5) | 443 (54.0) | 941 (61.5) | 774 (46.4) |
| Ethnicity, n (%) | ||||||
| Not Hispanic or Latino | 221 (82.8) | 226 (76.4) | 302 (83.2) | 767 (93.4) | 1400 (91.4) | 1502 (90.0) |
| Race, n (%) | ||||||
| American Indian/Alaskan Native | 0 | 2 (0.7) | 3 (0.8) | 6 (0.7) | 14 (0.9) | 22 (1.3) |
| Asian | 9 (3.4) | 6 (2.0) | 1 (0.3) | 90 (11.0) | 66 (4.3) | 16 (1.0) |
| Black/African American | 20 (7.5) | 42 (14.2) | 66 (18.2) | 16 (1.9) | 55 (3.6) | 116 (7.0) |
| Native Hawaiian/Pacific Islander | 0 | 2 (0.7) | 2 (0.6) | 1 (0.1) | 0 | 3 (0.2) |
| Caucasian | 234 (87.6) | 238 (80.4) | 283 (78.0) | 692 (84.3) | 1355 (88.5) | 1451 (86.9) |
| Multiracial | 4 (1.5) | 3 (1.0) | 6 (1.7) | 15 (1.8) | 38 (2.5) | 56 (3.4) |
| Unknown | 0 | 3 (1.0) | 2 (0.6) | 1 (0.1) | 3 (0.2) | 5 (0.3) |
| Age, years | ||||||
| Mean ± s.d. | 46.4 ± 15.10 | 48.9 ± 13.68 | 47.6 ± 12.92 | 44.9 ± 16.19 | 49.5 ± 13.40 | 47.3 ± 12.39 |
| Range | 18–86 | 18–85 | 20–76 | 18–90 | 18–87 | 19–84 |
| BMI, kg/m2 | ||||||
| Mean ± s.d. | 22.3 ± 1.86 | 27.4 ± 1.39 | 35.8 ± 5.87 | 22.6 ± 1.87 | 27.5 ± 1.41 | 35.4 ± 5.15 |
| Range | 17–25 | 25–30 | 30–71 | 14–25 | 25–30 | 30–81 |
| Alcohol drinker, n (%) | 160 (59.9) | 168 (56.8) | 181 (49.9) | 444 (54.1) | 921 (60.2) | 907 (54.4) |
| Smoker, n (%) | 55 (20.6) | 55 (18.6) | 58 (16.0) | 206 (25.1) | 375 (24.5) | 386 (23.1) |
| Caffeine user, n (%) | 211 (79.0) | 230 (77.7) | 309 (85.1) | 604 (73.6) | 1202 (78.6) | 1361 (81.6) |
| H. pylori status, n (%) | ||||||
| Positive | 68 (25.5) | 102 (34.5) | 101 (27.8) | 14 (1.7) | 18 (1.2) | 30 (1.8) |
| Negative | 198 (74.2) | 191 (64.5) | 260 (71.6) | 803 (97.8) | 1507 (98.4) | 1635 (98.0) |
| Unknown | 1 (0.4) | 3 (1.0) | 2 (0.6) | 4 (0.5) | 6 (0.4) | 4 (0.2) |
| Baseline Los Angeles Grade of EO, n (%) | ||||||
| A | 368 (44.8) | 537 (35.1) | 511 (30.6) | |||
| B | N/A | N/A | N/A | 271 (33.0) | 547 (35.7) | 623 (37.3) |
| C | 152 (18.5) | 363 (23.7) | 408 (24.4) | |||
| D | 30 (3.7) | 84 (5.5) | 127 (7.6) | |||
BMI, body mass index; EO, erosive oesophagitis; N/A, not applicable; NERD, non-erosive gastro-oesophageal reflux disease; s.d., standard deviation.
*
All patients with evaluable diary data and heartburn symptom severity data at baseline and during treatment were included in this analysis.