Table 1.
Differences in the Erythron Between C57Bl/6, β-Thalassemic, and Berkeley Mice. Asterisk (*) Indicates Statistically Different from Control, t-test, (P<0.05).
| Mouse Strain | Statistics | Reticulocytes | Mature Erythrocytes | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Retic (x109cells/L) | CHr (pg) | Retic_ RDW (%) | Retic_ HDW (g/dL) | RBC (x106/uL) | HGB (g/dL) | HCT (%) | RDW (%) | MCV (fL) | MCH (pg) | MCHC (g/dL) | HDW (g/dL) | ||
| C57BL/6 n=30 | Mean Std. Dev. | 304.59 ± 47.98 | 16.11 ± 0.30 | 11.61 ± 0.66 | 1.91 ± 0.09 | 9.74 ± 0.31 | 15.22 ± 0.43 | 53.42 ± 1.74 | 12.39 ± 1.18 | 54.86 ± 1.04 | 15.63 ± 0.29 | 28.49 ± 0.40 | 1.36 ± 0.04 |
| TH3+/C57BL/6 n=34 | Mean Std. Dev. | 1751.45* ± 388.28 | 13.97* ± 0.55 | 17.39* ± 1.11 | 3.64* ± 0.20 | 9.09* ± 0.65 | 8.94* ± 0.58 | 36.64* ± 1.95 | 34.51* ± 2.79 | 40.13* ± 1.72 | 9.81* ± 0.61 | 24.45* ± 1.18 | 4.27* ± 0.34 |
| Berkeley n=18 | Mean Std. Dev. | 1880.09* ± 453.38 | 13.93* ± 1.38 | 17.23* ± 2.34 | 3.35* ± 0.49 | 5.27* ± 1.12 | 5.59* ± 1.03 | 27.01* ± 3.87 | 25.16* ± 3.52 | 52.42 ± 7.87 | 10.91* ± 2.18 | 20.68* ± 1.57 | 3.57* ± 0.27 |