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. Author manuscript; available in PMC: 2014 Jan 23.
Published in final edited form as: Neuron. 2013 Jan 23;77(2):235–242. doi: 10.1016/j.neuron.2012.12.029

Table 1.

Population Distribution of Rare and Common LoFs

Average number
of homozygous
variants		 Number of
unique genes
with a
homozygous
variant		 Average number
of heterozygous
variants		 Number of
unique genes
with a
heterozygous
variant
Rare (≤5%) LoFs 0.05 variant per individual 33 genes 13 variants per individual 3,409 genes
Common (>5%) LoFs 5 variants per individual 96 genes 36 variants per individual 99 genes

The average number of rare (≤5%) and common (>5%) homozygous LoF variants, as well as the average number of such variants calculated from the BI case-control dataset.